<?xml version="1.0" encoding="UTF-8"?>
<!-- edited with XML Spy v4.2 U (http://www.xmlspy.com) by Henry Fang (BEA) -->
<!--DTD generated by XML Spy v4.2 U (http://www.xmlspy.com)-->
<!ELEMENT centre_activity (compound_code, protocol_code, centre_code, centre_activity_description, sequence, centre_activity_type, offset, screen_or_enrol_mark)>
<!ELEMENT centre_activity_description EMPTY>
<!ELEMENT centre_activity_type (centre_activity_type_code, centre_activity_type_description)>
<!ELEMENT centre_activity_type_code EMPTY>
<!ELEMENT centre_activity_type_description EMPTY>
<!ELEMENT centre_code (#PCDATA)>
<!ELEMENT centre_completion_date EMPTY>
<!ATTLIST centre_completion_date
	actual CDATA #REQUIRED
>
<!ELEMENT centre_initiation_date EMPTY>
<!ATTLIST centre_initiation_date
	actual CDATA #REQUIRED
>
<!ELEMENT clinical_program (clinical_program_code, clinical_program_description)>
<!ELEMENT clinical_program_code EMPTY>
<!ELEMENT clinical_program_description EMPTY>
<!ELEMENT clinical_research_associate (#PCDATA)>
<!ELEMENT commercial_research_organisation (cro_code, cro_description)>
<!ELEMENT completion_date EMPTY>
<!ELEMENT compound (compound_code, compound_number, compound_source, license_status, origin, protocol)>
<!ELEMENT compound_code (#PCDATA)>
<!ELEMENT compound_number (#PCDATA)>
<!ELEMENT compound_source (#PCDATA)>
<!ELEMENT contact EMPTY>
<!ELEMENT contact_mail (#PCDATA)>
<!ELEMENT control (control_code)>
<!ELEMENT control_code EMPTY>
<!ELEMENT country (country_code, country_description)>
<!ELEMENT country_code EMPTY>
<!ELEMENT country_description EMPTY>
<!ELEMENT cro_code (#PCDATA)>
<!ELEMENT cro_description (#PCDATA)>
<!ELEMENT cumlative_centre_enrol_flag EMPTY>
<!ELEMENT data_entry (site, system)>
<!ELEMENT data_expected_completed_patient EMPTY>
<!ELEMENT data_expected_enroled_dropout EMPTY>
<!ELEMENT data_expected_screening_dropout EMPTY>
<!ELEMENT dmpk_indicator EMPTY>
<!ELEMENT dosage (dosage_code, dosage_description)>
<!ELEMENT dosage_code EMPTY>
<!ELEMENT dosage_description EMPTY>
<!ELEMENT enrol_date (#PCDATA)>
<!ELEMENT enrolment_dropout_rate EMPTY>
<!ELEMENT final_code EMPTY>
<!ELEMENT final_flag EMPTY>
<!ELEMENT first_patient_enroled_date EMPTY>
<!ELEMENT fund_source (fund_source_code, fund_source_description)>
<!ELEMENT fund_source_code EMPTY>
<!ELEMENT fund_source_description EMPTY>
<!ELEMENT indication (indication_code, indication_description)>
<!ELEMENT indication_code EMPTY>
<!ELEMENT indication_description EMPTY>
<!ELEMENT interim_number EMPTY>
<!ELEMENT license_status EMPTY>
<!ELEMENT managing_country (country)>
<!ELEMENT number_evaluation_patients EMPTY>
<!ELEMENT office_code (#PCDATA)>
<!ELEMENT offset (unit_of_measure, value)>
<!ELEMENT origin (origin_code, origin_description)>
<!ELEMENT origin_code EMPTY>
<!ELEMENT origin_description EMPTY>
<!ELEMENT path_body (path_root)>
<!ELEMENT path_env (path_header, path_body)>
<!ELEMENT path_header (source_system, contact_mail, publish_date)>
<!ELEMENT path_root (compound)>
<!ELEMENT personnel EMPTY>
<!ELEMENT planned_enrolment (#PCDATA)>
<!ELEMENT planned_number_centres (#PCDATA)>
<!ELEMENT pmp_entity_code EMPTY>
<!ELEMENT principal_investigator (#PCDATA)>
<!ELEMENT protocol (compound_code, protocol_code, protocol_status, title, screening_dropout_rate, enrolment_dropout_rate, data_expected_completed_patient, data_expected_enroled_dropout, data_expected_screening_dropout, treatment_duration, dmpk_indicator, research_phase, study_duration, sequence, completion_date, final_flag, interim_number, final_code, route, dosage, fund_source, clinical_program, contact, indication, control, number_evaluation_patients, managing_country, remote_enrolment, cumlative_centre_enrol_flag, pmp_entity_code, first_patient_enroled_date, protocol_office, therapeutic_area)>
<!ELEMENT protocol_centre (compound_code, protocol_code, centre_code, protocol_centre_status, centre_initiation_date, centre_completion_date, commercial_research_organisation, principal_investigator, clinical_research_associate, personnel, data_entry, target_enrolment, subject+, centre_activity)>
<!ELEMENT protocol_centre_status (protocol_centre_status_code, protocol_centre_status_description)>
<!ELEMENT protocol_centre_status_code (#PCDATA)>
<!ELEMENT protocol_centre_status_description (#PCDATA)>
<!ELEMENT protocol_code (#PCDATA)>
<!ELEMENT protocol_country (compound_code, protocol_code, protocol_country_description, protocol_country_code, protocol_centre)>
<!ELEMENT protocol_country_code (#PCDATA)>
<!ELEMENT protocol_country_description (#PCDATA)>
<!ELEMENT protocol_office (protocol_office_description, compound_code, protocol_code, office_code, planned_number_centres, planned_enrolment, protocol_country)>
<!ELEMENT protocol_office_description (#PCDATA)>
<!ELEMENT protocol_status (protocol_status_code, protocol_status_description)>
<!ELEMENT protocol_status_code EMPTY>
<!ELEMENT protocol_status_description EMPTY>
<!ELEMENT publish_date (#PCDATA)>
<!ELEMENT remote_enrolment (remote_enrolment_code, remote_enrolment_description)>
<!ELEMENT remote_enrolment_code EMPTY>
<!ELEMENT remote_enrolment_description EMPTY>
<!ELEMENT research_phase (research_phase_code, research_phase_description)>
<!ELEMENT research_phase_code EMPTY>
<!ELEMENT research_phase_description EMPTY>
<!ELEMENT route (route_code, route_description)>
<!ELEMENT route_code EMPTY>
<!ELEMENT route_description EMPTY>
<!ELEMENT screen_date (#PCDATA)>
<!ELEMENT screen_or_enrol_mark (screen_or_enrol_mark_code, screen_or_enrol_mark_description)>
<!ELEMENT screen_or_enrol_mark_code EMPTY>
<!ELEMENT screen_or_enrol_mark_description EMPTY>
<!ELEMENT screening_dropout_rate EMPTY>
<!ELEMENT sequence EMPTY>
<!ELEMENT short EMPTY>
<!ELEMENT site (site_code, site_description)>
<!ELEMENT site_code (#PCDATA)>
<!ELEMENT site_description (#PCDATA)>
<!ELEMENT source_system (#PCDATA)>
<!ELEMENT study_duration EMPTY>
<!ELEMENT subject (compound_code, protocol_code, centre_code, subject_code, subject_status, screen_date, enrol_date)>
<!ELEMENT subject_code (#PCDATA)>
<!ELEMENT subject_status (subject_status_code, subject_status_description)>
<!ELEMENT subject_status_code (#PCDATA)>
<!ELEMENT subject_status_description (#PCDATA)>
<!ELEMENT system (system_code, system_description)>
<!ELEMENT system_code (#PCDATA)>
<!ELEMENT system_description (#PCDATA)>
<!ELEMENT target_enrolment EMPTY>
<!ELEMENT therapeutic_area (therapeutic_area_code)>
<!ELEMENT therapeutic_area_code EMPTY>
<!ELEMENT title (short)>
<!ELEMENT treatment_duration EMPTY>
<!ELEMENT unit_of_measure (unit_of_measure_code, unit_of_measure_description)>
<!ELEMENT unit_of_measure_code EMPTY>
<!ELEMENT unit_of_measure_description EMPTY>
<!ELEMENT value EMPTY>
